Protein name:
Integrin alpha-V ;
Alternative:
Vitronectin receptor subunit alpha ;
CD:
CD51 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with RAB25 (By similarity). Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8.
Function:
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. Mice expressing a null mutation of the alpha-V subunit gene survive until late in embryonic development and occasionally even to birth. They demonstrate cleft palate, and defective development of CNS and gastrointestinal blood vessels.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MAAPGRLLLR | PRPGGLLLLL | PGLLLPLADA | FNLDVESPAE | YAGPEGSYFG |
100:
FAVDFFEPST | SSRMFLLVGA | PKANTTQPGI | VEGGQVLKCE | CSSSRRCQPI |
150:
EFDSTGNRDY | AKDDPLEFKS | HQWFGASVRS | KQDKILACAP | LYHWRTEMKQ |
200:
EREPVGTCFL | QDGTKTVEYA | PCRSKNIDAD | GQGFCQGGFS | IDFTKADRVL |
250:
LGGPGSFYWQ | GQLISDQVAE | IISKYDPNVY | SIKYNNQLAT | RTAQAIFDDS |
300:
YLGYSVAVGD | FNGDGIEDFV | SGVPRAARTL | GMVYIYDGKN | MSSLHNFTGE |
350:
QMAAYFGFSV | AATDINGDDY | ADVFIGAPLF | MDRGSDGKLQ | EVGQVSVSLQ |
400:
RAVGDFQTTK | LNGFEVFARF | GSAIAPLGDL | DQDGFNDIAI | AAPYGGEDKK |
450:
GLVYIFNGRS | TGLNSVPSQI | LEGQWAAQSM | PPSFGYSMKG | ATDVDRNGYP |
500:
DLVVGAFGVD | RAVLYRARPV | VTVNAGLEVY | PSILNQDNKI | CPLPGTALKV |
550:
SCFNVRFCLK | ADGKGTLPRK | LHFQVELLLD | KLKQKGAIRR | ALFLHNRSPV |
600:
HSKTMTVFRG | GQMQCEELVA | YLRDESEFRD | KLTPITIFME | YRLDQRTAAD |
650:
ATGLQPILNQ | FTPANVSRQA | HILLDCGEDN | VCKPKLEVSV | NSDQKKIYIG |
700:
DDNPLTLTVK | AQNQGEGAYE | AELIVSIPPQ | ADFIGVVRNN | EALARLSCAF |
750:
KTENQTRQVV | CDLGNPMKAG | TQLLAGLRFS | VHQQSEMDTS | VKFDLKIQSS |
800:
NSFDNVSPVV | SYKVDLAVLA | AVEIRGVSSP | DHIFLPIPNW | EYKENPETEE |
850:
DVGPIVQHIY | ELRNNGPSSF | SKAILNLQWP | YKYNNNTLLY | ILHYDIDGPM |
900:
NCTADTEINP | LRIKTPEKND | TAAAGQGERN | HLITKRDLTL | REGDVHTLGC |
950:
GIAKCLQITC | QVGRLDRGKS | AILYVKSLLW | TETFMNKENQ | NHSYSLKSSA |
1000:
SFNIIEFPYK | NLPIEDLFNS | TLVTTNITWG | IQPAPMPVPV | WVIILAVLAG |
1044:
LLLLAVLVFV | MYRMGFFKRV | RPPQEEQERE | QLQPHENGEG | NSET
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
Chicken
ELISA Kit for Mouse Integrin alpha-V
ELISA Kit for Mouse Integrin alpha-V
ELISA Kit for Mouse Integrin alpha-V
ELISA Kit for Mouse Integrin alpha-V
CLIA Kit for Mouse Integrin alpha-V
CLIA Kit for Mouse Integrin alpha-V
CLIA Kit for Mouse Integrin alpha-V
CLIA Kit for Mouse Integrin alpha-V
Polyclonal Antibody for Mouse Integrin alpha-V
Polyclonal Antibody for Mouse Integrin alpha-V
Polyclonal Antibody for Mouse Integrin alpha-V
Polyclonal Antibody for Mouse Integrin alpha-V
Monoclonal Antibody for Mouse Integrin alpha-V
Monoclonal Antibody for Mouse Integrin alpha-V
Monoclonal Antibody for Mouse Integrin alpha-V
Monoclonal Antibody for Mouse Integrin alpha-V
Protein for Mouse Integrin alpha-V
Protein for Mouse Integrin alpha-V
Protein for Mouse Integrin alpha-V
Protein for Mouse Integrin alpha-V
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
CD-1 .
tissue :
Kidney .
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
3.
"The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
Gundry R.L.
,
Raginski K.
,
Tarasova Y.
,
Tchernyshyov I.
,
Bausch-Fluck D.
,
Elliott S.T.
,
Boheler K.R.
,
Van Eyk J.E.
,
Wollscheid B.
Mol. Cell. Proteomics8:2555-2569(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-74; ASN-615; ASN-869; ASN-939 AND ASN-941
tissue :
Myoblast .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-74; ASN-615 AND ASN-869